Generic Medicines: Are They worth the Risk of Making the Switch

Every year, people save an estimated $ 8 billion to $ 10 billion at retail pharmacies by buying generic drugs rather than brand-name medications, the Food and Drug Administration (FDA) reports. The lower cost, of course, is the key advantage of generics. But the real reason for the cost-savings that generic medicines should not suffer the big expensive clinical trials, which are necessary for the approval of branded drugs raises questions about the quality and safety of generic drugs.

Are these concerns justified? In such circumstances, it is safe to prescribe generic medicines, or to substitute a generic for a brand-name drug? Are brand-name drugs always better? To answer these questions, we conducted a thorough review of the evidence, which included numerous randomised controlled trials (RCTs) and case studies, as well as a unique meta-analysis that evaluated the benefits and risks of generic medications.

Generics: On the positive side

Safety and efficacy. Our literature search revealed little evidence that generic medicines are less safe or less effective than their brand-name counterparts. The meta-analysis, for example, included 47 studies (38 out of 47 were RCTs) covering 9 subclasses of cardiovascular medications. In studies involving beta blockers, diuretics, calcium channel blockers, antiplatelet agents, statins, angiotensin converting enzyme inhibitors and alpha-blockers, is no evidence of the superiority of generic drugs it was found vs brand.

Cost. Generic medicines typically cost 30% to 60% less than their branded counterparts, and the widespread use of generic drugs has the potential to reduce the price of other brand name drugs by creating more competition.

Another benefit: Patients taking generic medicines appear to be more willing to continue therapy than those treated with brand-name medications. Lower co-pays are a key factor. In one recent study of patients with high cholesterol or diabetes, those taking generic drugs had a greater adherence than patients treated with brand-name drugs.

Quality. It is important to note that many generic medicines are produced under license of the manufacturer of the original brand product, with low-cost equivalent often introduced after the drug's patent has expired. Even when several manufacturers to produce the brand name product and the generic, there are strict standards to ensure the quality of generics.

ABOUT US

Mediklik is a great online platform whether it is for getting an online health consultation, share your health records online, find the right specialist for your condition or know correct and upright information about diseases, medicines, surgical procedures and first-aid. This platform provides the one-stop platform for all your health.

Mediklik-Apka Health Buddy